Estimation and Hypothesis Testing of Derivatives in Smoothing Spline ANOVA Models

08/26/2023
by   Ruiqi Liu, et al.
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This article studies the derivatives in models that flexibly characterize the relationship between a response variable and multiple predictors, with goals of providing both accurate estimation and inference procedures for hypothesis testing. In the setting of tensor product reproducing spaces for nonparametric multivariate functions, we propose a plug-in kernel ridge regression estimator to estimate the derivatives of the underlying multivariate regression function under the smoothing spline ANOVA model. This estimator has an analytical form, making it simple to implement in practice. We first establish L_∞ and L_2 convergence rates of the proposed estimator under general random designs. For derivatives with some selected interesting orders, we provide an in-depth analysis establishing the minimax lower bound, which matches the L_2 convergence rate. Additionally, motivated by a wide range of applications, we propose a hypothesis testing procedure to examine whether a derivative is zero. Theoretical results demonstrate that the proposed testing procedure achieves the correct size under the null hypothesis and is asymptotically powerful under local alternatives. For ease of use, we also develop an associated bootstrap algorithm to construct the rejection region and calculate the p-value, and the consistency of the proposed algorithm is established. Simulation studies using synthetic data and an application to a real-world dataset confirm the effectiveness of our methods.

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